Sitazit-M 50/1000 Tablet Uses, Side effects

Sitazit-M 50/1000 Tablet uses, side effects, precautions

CompositionSitagliptin (50mg) + Metformin (1000mg)
CompanyGlenmark Pharmaceuticals Ltd
Medicine TypeAntidiabetic
Prescription requiredYes
Route of administrationOral
UsesType 2 Diabetes Mellitus
Side effectsNausea, Abdominal Pain, Diarrhea
PrecautionsHypersensitivity, Alcohol

General uses of Sitazit-M 50/1000 Tablet

Sitazit-M 50/1000 Tablet is a combination of two medicines. It is generally used to control the blood sugar (glucose) level in patients with type 2 diabetes mellitus.

Sitagliptin and metformin in this medicine work differently to control both fasting and postmeal blood sugar level in the body.

Ingredients of Sitazit-M 50/1000 Tablet

Sitagliptin: Sitazit-M 50/1000 Tablet contain sitagliptin (50mg). It belongs to the class of medicines known as DPP-4 inhibitors. It generally works by increasing insulin secretion from the pancreas and helps control blood glucose levels.

Metformin: It contains metformin (1000mg). Metformin belongs to the class of medications known as biguanides. It helps control blood glucose levels in patients having type 2 diabetes.

How does Sitazit-M 50/1000 Tablet work? / Mechanism of action

Sitagliptin in this tablet works by inhibiting the DPP-4 (Dipeptidyl Peptidase-4) enzyme. Inhibiting the DPP-4 enzyme inhibits the inactivation of incretins (GLP-4 and GIP). This result helps GLP-4 and GIP to secrete more insulin from the beta cells of the pancreas and eventually helps control the blood sugar (glucose) levels in the body.

While metformin in Sitazit-M 50/1000 Tablet works by:

  • Lowering the glucose output from the liver.
  • Decreasing intestinal absorption of glucose.
  • Improving the utilization of glucose in the body.

When Sitazit-M 50/1000 Tablet is prescribed?

Sitazit-M 50/1000 Tablet is usually prescribed in patients with type 2 diabetes mellitus to control the blood glucose levels.

Side effects of Sitazit-M 50/1000 Tablet

Sitazit-M 50/1000 Tablet may cause some side effects like:

  • Nausea
  • Abdominal Pain
  • Diarrhea
  • Loss of appetite
  • Dizziness
  • Headache
  • Hypoglycemia (low blood sugar level)
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Precautions

Alcohol: It is not advised to take alcohol with this medicine.

Hypersensitivity: You should avoid using this medicine if you are hypersensitive (allergic) to any of the ingredients of Sitazit-M 50/1000 Tablet.

Liver or kidney disease: This medicine should be used with caution in patients with any liver or kidney disease.

How to use Sitazit-M 50/1000 Tablet?

Take the dose of Sitazit-M 50/1000 Tablet as advised by your doctor.

It is best to take Sitazit-M 50/1000 Tablet with the meal.

Do not chew, crush, or break the tablet. Swallow it as a whole.

Storage of Sitazit-M 50/1000 Tablet

Store Sitazit-M 50/1000 Tablet at room temperature.

Keep this medicine away from kids and pets.

Keep this medicine away from direct sunlight.

Tell your doctor if:

  • You are allergic to sitagliptin or metformin.
  • You’ve any liver or kidney disease.
  • You are taking some other antidiabetic medications.

Some FAQs

What are the uses of Sitazit-M 50/1000 Tablet?

Sitazit-M 50/1000 Tablet is a combination of two medicines. It is generally used to control the blood glucose (sugar) level in patients with type 2 diabetes mellitus.

What is the dose and duration of Sitazit-M 50/1000 Tablet for adults?

For adults, Sitazit-M 50/1000 Tablet is usually prescribed one tablet 1-2 times a day. But the dose and duration of this medicine are not the same for all and depend on various factors. You should always consult your doctor about the dose and duration of this medicine.

What are the side effects of Sitazit-M 50/1000 Tablet?

Sitazit-M 50/1000 Tablet may cause some side effects like nausea, vomiting, loss of appetite, abdominal pain, and hypoglycemia (low blood sugar level).

Summary

Sitazit-M 50/1000 Tablet is an antidiabetic medicine that contains sitagliptin and metformin as its active ingredients. It is generally used to control the blood glucose level in patients with type 2 diabetes mellitus.

This medicine should be used with caution in patients with any liver or kidney disease.

Disclaimer: The information contained in pharmbaba.com is presented for the purpose of educating consumers. Nothing contained in pharmbaba.com is intended to be instructional for medical diagnosis or treatment. The information should not be considered complete, nor should it be relied on to suggest a course of treatment for a particular individual. Information obtained in pharmbaba.com is not exhaustive and does not cover all diseases, ailments, physical conditions, or their treatment.

Sahil Nasa (B. Pharma)
Sahil Nasa (B. Pharma)

Sahil is the founder of PharmBaba.com. He likes to read books and write blogs.