Neksium D 40 Capsule uses, side effects, precautions, substitutes
| Composition | Esomeprazole(40mg) + Domperidone(30mg) |
| Company | Pfizer Ltd |
| Medicine type | Proton pump inhibitor, Antiemetic(Prokinetic) |
| Prescription required | Yes |
| Route of administration | Oral |
| Uses | GERD, Peptic Ulcer, Acidity, Heartburn |
| Side effects | Diarrhea, Dizziness, Stomach Pain, Headache |
| Precautions | Pregnancy, Alcohol, Cardiovascular disease |
General uses of Neksium D 40 Capsule
Neksium D 40 Capsule is a combination of two medicine and is mainly used to treat symptoms of GERD(gastroesophageal reflux disease) and Peptic Ulcers.
It helps in relieving the symptoms such as stomach pain, heartburn, acidity, nausea, and gastric irritation.
It usually works by decreasing the amount of excess acid in the stomach.
Ingredients of Neksium D 40 Capsule
Esomeprazole: Neksium D 40 Capsule contains Esomeprazole(40mg). It is a class of medications known as proton pump inhibitors. It is mainly used to treat excessive acid formation in the stomach and helps in relieving symptoms like heartburn, acidity, gastric irritation.
Domperidone: It contains Domperidone(30mg). It is mainly a Dopamine antagonist and comes under the class of medicine known as antiemetic drugs. it is generally used to treat the symptoms of nausea and vomiting.
How does Neksium D 40 Capsule work? / Mechanism of action of Neksium D 40 Capsule
Neksium D 40 Capsule is a combination of two medicine. The Esomeprazole in Neksium D 40 Capsule is a proton pump inhibitor that works by inhibiting the H+/k+ ATP in the parietal cells of the stomach, which is the final step of acid formation. So it works by reducing stomach acid formation and helps in relieving the symptoms of GERD and Peptic ulcers.
The Domperidone in the Neksium D 40 Capsule is an antiemetic drug. It mainly works by stimulating the GIT peristalsis(increase the movement of stomach and intestine) and helps the food to easily move through the stomach and this in results causes stomach emptying.
The combination of Esomeprazole + Domperidone Is mainly used in the treatment of symptoms of GERD(Gastroesophageal reflux disease) and peptic ulcers.
When Neksium D 40 Capsule is prescribed?
GERD(Gastroesophageal Reflux Disease): It is a disease when the stomach acid flows back into the food pipe(esophagus). This stomach acid can irritate the lining of the esophagus. Neksium D 40 Capsule helps in reducing stomach acid formation and relieve GERD symptoms.
Nausea and Vomiting: Nausea and Vomiting are generally occurred due to digestive system disorders. Domperidone in Neksium D 40 Capsule increases the movement of the stomach and intestine and helps in stomach emptying. This in result helps in relieving symptoms of nausea and vomiting.
Peptic Ulcer: It is a condition when a sore develops in the small intestine, stomach, or esophagus. Neksium D 40 Capsule reduces stomach acid formation and helps the ulcer heal naturally. It also helps in relieving the symptoms of peptic ulcers such as nausea, vomiting, and bloating.
Side effects of Neksium D 40 Capsule
Neksium D 40 Capsule usually does not show any serious side effects. But in some cases, it may show side effects like:
- Diarrhea
- Dizziness
- Headache
- Stomach pain
- Dryness in mouth
Precautions
Pregnancy: Pregnant women should avoid the consumption of Neksium D 40 Capsule.
Cardiovascular Disease: It should be used with caution in patients with having any Cardiovascular(Heart-related) Disease.
Driving: It may cause dizziness and visual disturbance in some individuals. Avoid doing driving or operating heavy machinery after taking the dose of Neksium D 40 Capsule.
Hypersensitivity: Avoid using this medicine, if you are Hypersensitive(allergic) to any of the ingredients (Esomeprazole and Domperidone) of this Neksium D 40 Capsule.
Old Age Patients: Patients who are above the age of 60 should not consume Neksium D 40 Capsule
Alcohol: Avoid doing the consumption of alcohol with the use of this medicine.
Liver or Kidney Disease: Neksium D 40 Capsule should be used with caution in patients with having any liver or kidney disease.
How to use Neksium D 40 Capsule
Take the dose of Neksium D 40 Capsule as advised by your doctor.
It is best to take this medicine on an empty stomach.
Do not chew, crush, or break this medicine. Swallow it as a whole.
Storage of Neksium D 40 Capsule
Store the Neksium D 40 Capsule in a cool and dry place.
Keep this medicine away from direct sunlight.
Keep this medicine away from pets and kids.
Substitutes of Neksium D 40 Capsule
| Nexpro RD 40 Capsule | Torrent Pharmaceuticals Ltd |
| Esomac D 40 Capsule | Cipla Ltd |
| Esogress-D Capsule | La Renon Healthcare Pvt Ltd |
| Esofine DSR Capsule | Macleods Pharmaceuticals Pvt Ltd |
| Lupisoz-D Capsule | Lupin Ltd |
| Esofag-D Capsule | Micro Labs Ltd |
Some FAQs
Neksium D 40 Capsule is mainly used in the treatment of symptoms of GERD(gastroesophageal reflux disease), and peptic ulcers like Heartburn, Acidity, Gastric Irritation, Nausea, and Vomiting.
It is not safe to use the Neksium D 40 Capsule during pregnancy.
The best time to take the Neksium D 40 Capsule is on an empty stomach.
Neksium D 40 Capsule may be harmful to those who are hypersensitive(allergic) to the Domperidone and Esomeprazole. It should be used with caution in patients with having any Cardiovascular, Liver, or Kidney disease.
Neksium D 40 Capsule is generally prescribed 1-2 times a day before having a meal. But the dose of this medicine is not the same for all. You should always consult the doctor about the dose of this medicine.
Each Neksium D 40 Capsule Contains Esomeprazole(40mg) and Domperidone(30mg).
Summary
Neksium D 40 Capsule is a combination of two medicines i.e. Esomeprazole and Domperidone. It is mainly used in the treatment of symptoms of GERD, and Peptic ulcers such as Acidity, Gastric Irritation, Heartburn, Nausea, and Vomiting.
Esomeprazole in this medicine is a proton pump inhibitor that helps in reducing the excess formation of the acid in the stomach and the Domperidone in this medicine is a dopamine antagonist, which helps in increasing the movement of food in the stomach and helps in stomach emptying.
This medicine should not be used in pregnancy.
It should be used with caution in patients with having any cardiovascular, liver, or kidney disease.
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