Neksium D 40 Capsule Uses, Side effects, Precautions

Share your love

Neksium D 40 Capsule uses, side effects, precautions, substitutes

CompositionEsomeprazole(40mg) + Domperidone(30mg)
CompanyPfizer Ltd
Medicine typeProton pump inhibitor, Antiemetic(Prokinetic)
Prescription requiredYes
Route of administrationOral
UsesGERD, Peptic Ulcer, Acidity, Heartburn
Side effectsDiarrhea, Dizziness, Stomach Pain, Headache
PrecautionsPregnancy, Alcohol, Cardiovascular disease

General uses of Neksium D 40 Capsule

Neksium D 40 Capsule is a combination of two medicine and is mainly used to treat symptoms of GERD(gastroesophageal reflux disease) and Peptic Ulcers.

It helps in relieving the symptoms such as stomach pain, heartburn, acidity, nausea, and gastric irritation.

It usually works by decreasing the amount of excess acid in the stomach.

Ingredients of Neksium D 40 Capsule

Esomeprazole: Neksium D 40 Capsule contains Esomeprazole(40mg). It is a class of medications known as proton pump inhibitors. It is mainly used to treat excessive acid formation in the stomach and helps in relieving symptoms like heartburn, acidity, gastric irritation.

Domperidone: It contains Domperidone(30mg). It is mainly a Dopamine antagonist and comes under the class of medicine known as antiemetic drugs. it is generally used to treat the symptoms of nausea and vomiting.

How does Neksium D 40 Capsule work? / Mechanism of action of Neksium D 40 Capsule

Neksium D 40 Capsule is a combination of two medicine. The Esomeprazole in Neksium D 40 Capsule is a proton pump inhibitor that works by inhibiting the H+/k+ ATP in the parietal cells of the stomach, which is the final step of acid formation. So it works by reducing stomach acid formation and helps in relieving the symptoms of GERD and Peptic ulcers.

The Domperidone in the Neksium D 40 Capsule is an antiemetic drug. It mainly works by stimulating the GIT peristalsis(increase the movement of stomach and intestine) and helps the food to easily move through the stomach and this in results causes stomach emptying.

The combination of Esomeprazole + Domperidone Is mainly used in the treatment of symptoms of GERD(Gastroesophageal reflux disease) and peptic ulcers.

When Neksium D 40 Capsule is prescribed?

GERD(Gastroesophageal Reflux Disease): It is a disease when the stomach acid flows back into the food pipe(esophagus). This stomach acid can irritate the lining of the esophagus. Neksium D 40 Capsule helps in reducing stomach acid formation and relieve GERD symptoms.

Nausea and Vomiting: Nausea and Vomiting are generally occurred due to digestive system disorders. Domperidone in Neksium D 40 Capsule increases the movement of the stomach and intestine and helps in stomach emptying. This in result helps in relieving symptoms of nausea and vomiting.

Peptic Ulcer: It is a condition when a sore develops in the small intestine, stomach, or esophagus. Neksium D 40 Capsule reduces stomach acid formation and helps the ulcer heal naturally. It also helps in relieving the symptoms of peptic ulcers such as nausea, vomiting, and bloating.

Side effects of Neksium D 40 Capsule

Neksium D 40 Capsule usually does not show any serious side effects. But in some cases, it may show side effects like:

  • Diarrhea
  • Dizziness
  • Headache
  • Stomach pain
  • Dryness in mouth

Precautions

Pregnancy: Pregnant women should avoid the consumption of Neksium D 40 Capsule.

Cardiovascular Disease: It should be used with caution in patients with having any Cardiovascular(Heart-related) Disease.

Driving: It may cause dizziness and visual disturbance in some individuals. Avoid doing driving or operating heavy machinery after taking the dose of Neksium D 40 Capsule.

Hypersensitivity: Avoid using this medicine, if you are Hypersensitive(allergic) to any of the ingredients (Esomeprazole and Domperidone) of this Neksium D 40 Capsule.

Old Age Patients: Patients who are above the age of 60 should not consume Neksium D 40 Capsule

Alcohol: Avoid doing the consumption of alcohol with the use of this medicine.

Liver or Kidney Disease: Neksium D 40 Capsule should be used with caution in patients with having any liver or kidney disease.

How to use Neksium D 40 Capsule

Take the dose of Neksium D 40 Capsule as advised by your doctor.

It is best to take this medicine on an empty stomach.

Do not chew, crush, or break this medicine. Swallow it as a whole.

Storage of Neksium D 40 Capsule

Store the Neksium D 40 Capsule in a cool and dry place.

Keep this medicine away from direct sunlight.

Keep this medicine away from pets and kids.

Substitutes of Neksium D 40 Capsule

Nexpro RD 40 CapsuleTorrent Pharmaceuticals Ltd
Esomac D 40 CapsuleCipla Ltd
Esogress-D CapsuleLa Renon Healthcare Pvt Ltd
Esofine DSR CapsuleMacleods Pharmaceuticals Pvt Ltd
Lupisoz-D CapsuleLupin Ltd
Esofag-D CapsuleMicro Labs Ltd

Some FAQs

What are the uses of Neksium D 40 Capsule?

Neksium D 40 Capsule is mainly used in the treatment of symptoms of GERD(gastroesophageal reflux disease), and peptic ulcers like Heartburn, Acidity, Gastric Irritation, Nausea, and Vomiting.

Is it safe to use Neksium D 40 Capsule during pregnancy?

It is not safe to use the Neksium D 40 Capsule during pregnancy.

What is the best time to take the Neksium D 40 Capsule?

The best time to take the Neksium D 40 Capsule is on an empty stomach.

What are the contraindications of Neksium D 40 Capsule?

Neksium D 40 Capsule may be harmful to those who are hypersensitive(allergic) to the Domperidone and Esomeprazole. It should be used with caution in patients with having any Cardiovascular, Liver, or Kidney disease.

What is the dose of Neksium D 40 Capsule for adults?

Neksium D 40 Capsule is generally prescribed 1-2 times a day before having a meal. But the dose of this medicine is not the same for all. You should always consult the doctor about the dose of this medicine.

What is the Composition of Neksium D 40 Capsule?

Each Neksium D 40 Capsule Contains Esomeprazole(40mg) and Domperidone(30mg).

Summary

Neksium D 40 Capsule is a combination of two medicines i.e. Esomeprazole and Domperidone. It is mainly used in the treatment of symptoms of GERD, and Peptic ulcers such as Acidity, Gastric Irritation, Heartburn, Nausea, and Vomiting.

Esomeprazole in this medicine is a proton pump inhibitor that helps in reducing the excess formation of the acid in the stomach and the Domperidone in this medicine is a dopamine antagonist, which helps in increasing the movement of food in the stomach and helps in stomach emptying.

This medicine should not be used in pregnancy.

It should be used with caution in patients with having any cardiovascular, liver, or kidney disease.

Disclaimer: The information contained in pharmbaba.com is presented for the purpose of educating consumers. Nothing contained in pharmbaba.com is intended to be instructional for medical diagnosis or treatment. The information should not be considered complete, nor should it be relied on to suggest a course of treatment for a particular individual. Information obtained in pharmbaba.com is not exhaustive and does not cover all diseases, ailments, physical conditions, or their treatment.

Share your love
Default image
Sahil Nasa (B. Pharma)
Sahil is the founder of PharmBaba.com. He likes to read books and write blogs.