Drofem Tablet Uses, Side effects, Precautions

Drofem Tablet uses, side effects, precautions, substitutes

CompositionDrotaverine (80mg) + Mefenamic acid (250mg)
CompanyFDC Ltd
Medicine typeAntispasmodic, Analgesic
Prescription requiredYes
Route of administrationOral
UsesAbdominal pain, Menstrual pain
Side effectsDizziness, Nausea, Constipation
PrecautionsLiver disease, Pregnancy, Alcohol

General uses of Drofem Tablet

Drofem Tablet is generally prescribed for the treatment of abdominal pain and menstrual (period-related) pain.

It helps in relieving spasms of the muscles in the stomach and intestines and can also be used to treat abdominal pain and cramps associated with irritable bowel syndrome.

Ingredients of Drofem Tablet

Drotaverine: Drofem Tablet contains drotaverine (80mg). It belongs to the class of drugs known as antispasmodics. It is mainly used in the treatment of muscle spasms in the GIT (gastrointestinal tract).

Mefenamic acid: It contains mefenamic acid (250mg). Mefenamic acid belongs to the class of medicines known as NSAIDs (non-steroidal anti-inflammatory drugs). It is mainly used in the treatment of pain and inflammation.

How does Drofem Tablet work? / Mechanism of action

Drotaverine in Drofem Tablet works by inhibiting the phosphodiesterase-4 (PDE-4) enzyme. Inhibiting the PDE-4 enzyme help elevates the levels of cAMP, which leads to the relaxation of the smooth muscles in the stomach and intestines and helps treat abdominal pain, cramps, and muscle spasms.

Mefenamic acid in this medicine works by inhibiting the synthesis of prostaglandins by blocking the activity of the cyclooxygenase (COX) enzyme. Blocking the synthesis of prostaglandins helps in relieving the symptoms of pain and inflammation.

Side effects of Drofem Tablet

In general, it does not show any serious side effects. But in some cases, it may show some side effects like:

  • Dizziness
  • Nausea
  • Constipation
  • Flushing
  • Headache
  • Dryness in mouth
  • Vomiting

Precautions

Hypersensitivity: You should avoid taking this medicine if you are hypersensitive (allergic) to any of the ingredients of the Drofem Tablet.

Alcohol: You should avoid taking Drofem Tablet with alcohol.

Pregnancy and breastfeeding: This medicine should be used with caution in pregnant and lactating women.

Liver or Kidney disease: Drofem Tablet should be used with caution in patients with any liver or kidney disease.

How to use Drofem Tablet?

Take the dose of Drofem Tablet as advised by your doctor.

It is best to take this medicine after having a meal.

Do not chew, crush, or break the tablet. Swallow it as a whole.

Storage

Store Drofem Tablet at room temperature.

Keep this medicine away from direct sunlight.

Keep this medicine away from kids and pets.

Tell your doctor if:

  • You are allergic to any of the ingredients of the Drofem Tablet.
  • You are a pregnant or breastfeeding mother.
  • You’ve any liver or kidney disease.

Substitutes of Drofem Tablet

Drotikind-M TabletMankind Pharma Ltd
Drotin-M TabletWalter Bushnell
Tavera-M TabletLeeford Healthcare Ltd
Spurge TabletObsurge Biotech Ltd
Spasmindon N TabletZydus Cadila

Some FAQs

What are the uses of the Drofem Tablet?

Drofem Tablet is a prescription medicine. It is mainly used in the treatment of menstrual pain, abdominal pain, and muscle spasm. It is also used to treat the symptoms associated with IBS (irritable bowel syndrome).

Can I use Drofem Tablet during pregnancy?

No, it is not advised to use Drofem Tablet during pregnancy.

What is the dose and duration of Drofem Tablet for adults?

For adults, Drofem Tablet can be prescribed one tablet 1-3 times a day. But the dose and duration of this medicine are not the same for all and depend on various factors. You should always consult your doctor about the dose and duration of this medicine.

Summary

Drofem Tablet is a combination of two medicines i.e. mefenamic acid and drotaverine. It is mainly used in the treatment of abdominal pain, menstrual cramps, and muscle spasms in the GIT (gastrointestinal tract).

This medicine should be used with caution in patients with any liver or kidney disease.

Disclaimer: The information contained in pharmbaba.com is presented for the purpose of educating consumers. Nothing contained in pharmbaba.com is intended to be instructional for medical diagnosis or treatment. The information should not be considered complete, nor should it be relied on to suggest a course of treatment for a particular individual. Information obtained in pharmbaba.com is not exhaustive and does not cover all diseases, ailments, physical conditions, or their treatment.