Drofem Tablet uses, side effects, precautions, substitutes
|Composition||Drotaverine (80mg) + Mefenamic acid (250mg)|
|Medicine type||Antispasmodic, Analgesic|
|Route of administration||Oral|
|Uses||Abdominal pain, Menstrual pain|
|Side effects||Dizziness, Nausea, Constipation|
|Precautions||Liver disease, Pregnancy, Alcohol|
General uses of Drofem Tablet
Drofem Tablet is generally prescribed for the treatment of abdominal pain and menstrual (period-related) pain.
It helps in relieving spasms of the muscles in the stomach and intestines and can also be used to treat abdominal pain and cramps associated with irritable bowel syndrome.
Ingredients of Drofem Tablet
Drotaverine: Drofem Tablet contains drotaverine (80mg). It belongs to the class of drugs known as antispasmodics. It is mainly used in the treatment of muscle spasms in the GIT (gastrointestinal tract).
Mefenamic acid: It contains mefenamic acid (250mg). Mefenamic acid belongs to the class of medicines known as NSAIDs (non-steroidal anti-inflammatory drugs). It is mainly used in the treatment of pain and inflammation.
How does Drofem Tablet work? / Mechanism of action
Drotaverine in Drofem Tablet works by inhibiting the phosphodiesterase-4 (PDE-4) enzyme. Inhibiting the PDE-4 enzyme help elevates the levels of cAMP, which leads to the relaxation of the smooth muscles in the stomach and intestines and helps treat abdominal pain, cramps, and muscle spasms.
Mefenamic acid in this medicine works by inhibiting the synthesis of prostaglandins by blocking the activity of the cyclooxygenase (COX) enzyme. Blocking the synthesis of prostaglandins helps in relieving the symptoms of pain and inflammation.
Side effects of Drofem Tablet
In general, it does not show any serious side effects. But in some cases, it may show some side effects like:
- Dryness in mouth
Hypersensitivity: You should avoid taking this medicine if you are hypersensitive (allergic) to any of the ingredients of the Drofem Tablet.
Alcohol: You should avoid taking Drofem Tablet with alcohol.
Pregnancy and breastfeeding: This medicine should be used with caution in pregnant and lactating women.
Liver or Kidney disease: Drofem Tablet should be used with caution in patients with any liver or kidney disease.
How to use Drofem Tablet?
Take the dose of Drofem Tablet as advised by your doctor.
It is best to take this medicine after having a meal.
Do not chew, crush, or break the tablet. Swallow it as a whole.
Store Drofem Tablet at room temperature.
Keep this medicine away from direct sunlight.
Keep this medicine away from kids and pets.
Tell your doctor if:
- You are allergic to any of the ingredients of the Drofem Tablet.
- You are a pregnant or breastfeeding mother.
- You’ve any liver or kidney disease.
Substitutes of Drofem Tablet
|Drotikind-M Tablet||Mankind Pharma Ltd|
|Drotin-M Tablet||Walter Bushnell|
|Tavera-M Tablet||Leeford Healthcare Ltd|
|Spurge Tablet||Obsurge Biotech Ltd|
|Spasmindon N Tablet||Zydus Cadila|
Drofem Tablet is a prescription medicine. It is mainly used in the treatment of menstrual pain, abdominal pain, and muscle spasm. It is also used to treat the symptoms associated with IBS (irritable bowel syndrome).
No, it is not advised to use Drofem Tablet during pregnancy.
For adults, Drofem Tablet can be prescribed one tablet 1-3 times a day. But the dose and duration of this medicine are not the same for all and depend on various factors. You should always consult your doctor about the dose and duration of this medicine.
Drofem Tablet is a combination of two medicines i.e. mefenamic acid and drotaverine. It is mainly used in the treatment of abdominal pain, menstrual cramps, and muscle spasms in the GIT (gastrointestinal tract).
This medicine should be used with caution in patients with any liver or kidney disease.
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